MIBG scintigraphy for differentiating Parkinson's disease with autonomic dysfunction from Parkinsonism‐predominant multiple system atrophy
Identifieur interne : 000A41 ( Main/Exploration ); précédent : 000A40; suivant : 000A42MIBG scintigraphy for differentiating Parkinson's disease with autonomic dysfunction from Parkinsonism‐predominant multiple system atrophy
Auteurs : Eun Joo Chung [Corée du Sud] ; Won Yong Lee [Corée du Sud] ; Won Tae Yoon [Corée du Sud] ; Byeong Joon Kim [Corée du Sud] ; Gyeong Han Lee [Corée du Sud]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-08-15.
English descriptors
- KwdEn :
Abstract
Parkinson's disease (PD) with autonomic dysfunction is difficult to differentiate from Parkinsonism‐predominant multiple system atrophy (MSA‐p). This study aimed to analyze the validity of MIBG scintigraphy for PD with autonomic dysfunction and MSA‐p. Thirty‐nine patients (PD: 27 patients, MSA‐p type: 12) and 12 age‐matched controls were prospectively enrolled and underwent MIBG scintigraphy and autonomic function test (AFT). We separately calculated early and delayed heart‐to‐mediastinal (H/M) ratio and washout rates (WRs). AFT was composed of sympathetic skin reflex and parasympathetic tests based on heart rate variability. Abnormal AFT was observed in 17 (63%) of PD and 10 (83%) of MSA‐p. On comparing PD with abnormal AFT with MSA‐p, either the early or delayed H/M ratio in PD was not different from that in MSA‐p (P > 0.05). Only the WR could differentiate PD with abnormal AFT from MSA‐p (47.07 ± 57.48 vs. 31.39 ± 31.52, respectively) (P = 0.026). According to the results, WR may be more useful than the early and delayed H/M ratio to distinguish MSA‐p from PD with abnormal AFT. Furthermore, the MIBG uptake did not reflect the disease duration or severity. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22649
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">MIBG scintigraphy for differentiating Parkinson's disease with autonomic dysfunction from Parkinsonism‐predominant multiple system atrophy</title><author><name sortKey="Chung, Eun Joo" sort="Chung, Eun Joo" uniqKey="Chung E" first="Eun Joo" last="Chung">Eun Joo Chung</name></author><author><name sortKey="Lee, Won Yong" sort="Lee, Won Yong" uniqKey="Lee W" first="Won Yong" last="Lee">Won Yong Lee</name></author><author><name sortKey="Yoon, Won Tae" sort="Yoon, Won Tae" uniqKey="Yoon W" first="Won Tae" last="Yoon">Won Tae Yoon</name></author><author><name sortKey="Kim, Byeong Joon" sort="Kim, Byeong Joon" uniqKey="Kim B" first="Byeong Joon" last="Kim">Byeong Joon Kim</name></author><author><name sortKey="Lee, Gyeong Han" sort="Lee, Gyeong Han" uniqKey="Lee G" first="Gyeong Han" last="Lee">Gyeong Han Lee</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:85DD3D3795A4A246C55B100870EF0ACAA50A2EAD</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1002/mds.22649</idno><idno type="url">https://api.istex.fr/document/85DD3D3795A4A246C55B100870EF0ACAA50A2EAD/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">002186</idno><idno type="wicri:Area/Main/Curation">001E77</idno><idno type="wicri:Area/Main/Exploration">000A41</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">MIBG scintigraphy for differentiating Parkinson's disease with autonomic dysfunction from Parkinsonism‐predominant multiple system atrophy</title><author><name sortKey="Chung, Eun Joo" sort="Chung, Eun Joo" uniqKey="Chung E" first="Eun Joo" last="Chung">Eun Joo Chung</name><affiliation wicri:level="1"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Inje University Pusan Baik Hospital, Pusan</wicri:regionArea><wicri:noRegion>Pusan</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Won Yong" sort="Lee, Won Yong" uniqKey="Lee W" first="Won Yong" last="Lee">Won Yong Lee</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Yoon, Won Tae" sort="Yoon, Won Tae" uniqKey="Yoon W" first="Won Tae" last="Yoon">Won Tae Yoon</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Kim, Byeong Joon" sort="Kim, Byeong Joon" uniqKey="Kim B" first="Byeong Joon" last="Kim">Byeong Joon Kim</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Lee, Gyeong Han" sort="Lee, Gyeong Han" uniqKey="Lee G" first="Gyeong Han" last="Lee">Gyeong Han Lee</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2009-08-15">2009-08-15</date><biblScope unit="volume">24</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="1650">1650</biblScope><biblScope unit="page" to="1655">1655</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">85DD3D3795A4A246C55B100870EF0ACAA50A2EAD</idno><idno type="DOI">10.1002/mds.22649</idno><idno type="ArticleID">MDS22649</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>MIBG scintigraphy</term><term>MSA‐p</term><term>Parkinson's disease</term><term>autonomic dysfunction</term><term>autonomic function test</term><term>multiple system atrophy</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Parkinson's disease (PD) with autonomic dysfunction is difficult to differentiate from Parkinsonism‐predominant multiple system atrophy (MSA‐p). This study aimed to analyze the validity of MIBG scintigraphy for PD with autonomic dysfunction and MSA‐p. Thirty‐nine patients (PD: 27 patients, MSA‐p type: 12) and 12 age‐matched controls were prospectively enrolled and underwent MIBG scintigraphy and autonomic function test (AFT). We separately calculated early and delayed heart‐to‐mediastinal (H/M) ratio and washout rates (WRs). AFT was composed of sympathetic skin reflex and parasympathetic tests based on heart rate variability. Abnormal AFT was observed in 17 (63%) of PD and 10 (83%) of MSA‐p. On comparing PD with abnormal AFT with MSA‐p, either the early or delayed H/M ratio in PD was not different from that in MSA‐p (P > 0.05). Only the WR could differentiate PD with abnormal AFT from MSA‐p (47.07 ± 57.48 vs. 31.39 ± 31.52, respectively) (P = 0.026). According to the results, WR may be more useful than the early and delayed H/M ratio to distinguish MSA‐p from PD with abnormal AFT. Furthermore, the MIBG uptake did not reflect the disease duration or severity. © 2009 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Corée du Sud</li></country><settlement><li>Séoul</li></settlement></list><tree><country name="Corée du Sud"><noRegion><name sortKey="Chung, Eun Joo" sort="Chung, Eun Joo" uniqKey="Chung E" first="Eun Joo" last="Chung">Eun Joo Chung</name></noRegion><name sortKey="Kim, Byeong Joon" sort="Kim, Byeong Joon" uniqKey="Kim B" first="Byeong Joon" last="Kim">Byeong Joon Kim</name><name sortKey="Lee, Gyeong Han" sort="Lee, Gyeong Han" uniqKey="Lee G" first="Gyeong Han" last="Lee">Gyeong Han Lee</name><name sortKey="Lee, Won Yong" sort="Lee, Won Yong" uniqKey="Lee W" first="Won Yong" last="Lee">Won Yong Lee</name><name sortKey="Yoon, Won Tae" sort="Yoon, Won Tae" uniqKey="Yoon W" first="Won Tae" last="Yoon">Won Tae Yoon</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A41 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000A41 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:85DD3D3795A4A246C55B100870EF0ACAA50A2EAD
|texte= MIBG scintigraphy for differentiating Parkinson's disease with autonomic dysfunction from Parkinsonism‐predominant multiple system atrophy
}}
| This area was generated with Dilib version V0.6.23. |  |